Chemistry Seminar: Arthur Glasfeld, Ph.D. "Metal Chaperones: Preventing Improper Interactions in the Cell”

Arthur Glasfeld has been teaching at Reed since 1989.  His main research interests are in protein structure and the structural basis for recognition and regulation of metal ions in the bacterial cell.  He spent the 2019-20 academic year (or most of it) in Durham, England learning to work in a glove box before being chased home by the virus to spend lockdown in an undisclosed, but oxygen-rich, location near the Reed canyon

"Metal Chaperones: Preventing Improper Interactions in the Cell”

Abstract: The cellular environment is crowded and complex.  Essential metal ions must find their way to the places they’re needed, without being distracted by inappropriate opportunities.  Zinc is problematic because none is in the free state inside a cell although it is generally the most abundant transition metal present. Until recently, mechanisms for zinc transport and delivery within in the cell were unknown.  My research over the past year explored a proposed bacterial “zinc chaperone” that could aid in zinc delivery to appropriate sites within the cell. In collaboration with my host lab at Durham University, we identified the protein conclusively as a zinc chaperone and have begun work to understand its mechanism and the role it plays in the overall metabolism of the cell.
 

Dial-In Information

This seminar is open to the public. Email johnstonk@reed.edu for the Zoom password.

Thursday, September 17, 2020 at 4:15pm to 5:00pm

Virtual Event
Event Type

Lecture

Audience

Faculty, Students, Alumni, Open to the Public, Parents & Family, Staff, Prospective Students

Department
Chemistry
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