Biology Seminar: Dr. David Booth, “Building a Simple Model of Animal Multicellularity”

David S. Booth,
Department of Molecular and Cell Biology, University of California, Berkeley

Building a Simple Model of Animal Multicellularity”

Friday, April 12, 2019
4:10 pm Seminar begins

Biology 19

Student Lunch: Email Kristy Gonyer at if you would like to go to lunch with Dr. Booth on Friday at noon.

Abstract: By comparing animals to their closest living relatives, the choanoflagellates, we can reconstruct the biology of animal ancestors to illuminate how cellular and genetic changes contributed to the origin of animal development. Importantly, choanoflagellates express genes that are otherwise only found in animals, suggesting that the cellular and genetic foundations of animal development were in place before the emergence of animals. Furthermore, choanoflagellates differentiate into distinct cell types and morphologies, including multicellular colonies that resemble early stages of animal embryogenesis. Previously, the absence of reverse genetic tools in choanoflagellates stunted functional comparisons between choanoflagellates and animals. With the first tools that I have developed for performing transgenics, genome editing, and functional genomics, I will explain how a choanoflagellate species, Salpingoeca rosetta, now serves a simple model for investigating the origin and evolution of animal multicellularity.

Additional Biology Department seminars can be found on-line, including links to some speakers' home pages at:

Friday, April 12, 2019 at 4:10pm to 5:00pm

Biology, Biology 19
3203 Southeast Woodstock Boulevard, Portland, Oregon 97202-8199

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Faculty, Students, Alumni, Open to the Public, Parents & Family, Staff, Prospective Students


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