This Friday's Biology Department Seminar:
Kristen Kwan, Ph.D, University of Utah
“Cellular & Molecular Dynamics Shaping the Vertebrate Eye”
Friday, April 21, 2017
3:50 pm Pre-seminar tea
4:10 pm Seminar begins
Abstract: Precise and stereotyped 3-dimensional tissue structure is essential for proper organ function. This structure is established during the process of morphogenesis, during which cells and tissues rearrange and organize themselves. Understanding morphogenesis has implications for understanding birth defects, as well as for building tissues and organs for regenerative medicine. In the case of the eye, improper structural development can lead to visual impairment and blindness. Despite increasing knowledge of pathways controlling the differentiation of many cell types in the eye, we still lack a basic understanding of the cell biological and developmental mechanisms controlling its morphogenesis. In the Kwan lab, we use a combination of 4-dimensional timelapse imaging, computational approaches, and zebrafish molecular genetics to determine the cellular and molecular basis for the morphogenesis of the optic cup, the initial embryonic eye structure. In this seminar, I will discuss two stories: the first will be about a role for the conserved Hedgehog signaling pathway in controlling the morphogenesis of a crucial eye structure, the choroid fissure; and the second will be about the role of the neural crest, an extrinsic, migratory cell population, in directing optic cup morphogenesis.
Any questions may be addressed directly with Professor Sarah Schaack, 2016-17 Coordinator, Biology Department Seminar Program via e-mail or phone (X7948).
Additional Biology Department seminars can be found on-line, including links to some speakers' home pages at: http://academic.reed.edu/biology/seminars/index.html
Friday, April 21 at 4:10pm to 5:00pm
Biology, Biology 19
3203 Southeast Woodstock Boulevard, Portland, Oregon 97202-8199